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Get to know the omentum: The apron of fat that protects your abdomen

The omentum's immune functions come from groups of small, white filters located among the fat cells. Anatomists first discovered these cell clusters in rabbits around 1874, giving them the name milky spots. Recent research has shown that they aid the omentum by collecting information about the health of the abdominal cavity. While the size and shape of the omentum varies, milky spots speckle the entire tissue and serve as a filter for surrounding fluid. "The fluid around the abdominal organs doesn't just sit there, it circulates through the milky spots," says Troy D. Randall, a clinical immunologist at the University of Alabama at Birmingham, who co-wrote the review with postdoctoral fellow Selene Meza-Perez. "Milky spots collect cells, antigens, and bacteria before deciding what's going to happen immunologically." The milky spots' analyses cause the omentum to respond immunologically by releasing inflammatory molecules, tolerating the presenc...

Simple step to protect people with type 1 diabetes against heart disease

A small preliminary clinical trial published in Diabetes and Vascular Disease Research has found the easy step allows people with type 1 diabetes to better regulate their blood sugar levels. Crucially, it also reduces fat and inflammatory markers in the blood that can damage blood vessels and heart disease. People with type 1 diabetes are up to ten times more likely to suffer from cardiovascular disease than the general population, and the condition accounts for more than half of all deaths in this patient group. The team are now looking to continue with a larger trial over a longer period to look at blood vessel health and diabetes control. In the UK, most people with type 1 diabetes regulate their blood sugar levels by injecting insulin throughout the day. The dose after mealtimes is usually calculated from the amount of carbohydrate in the meal. But this doesn't account for how much fat is in the food, which is broken down by the body at a slower rate than carbohydrate. ...

Two interventions help improve weight management in children with overweight or obesity

More and more we recognize that, if we don't assist families in tackling the social and environmental conditions that impede their ability to make changes to their obesity-related behaviors, we will not be successful in pediatric weight management," says Elsie Taveras, MD, MPH, chief of General Pediatrics at MassGeneral Hospital for Children, who led the study. "To help us create our interventions we looked to families with children who had managed to improve their BMI, often under challenging environmental and social settings. These "positive outlier" families provided guidance on the content of health coaching, available resources in the community, language to use in motivating other families to change and the importance of building parents' confidence in taking on the challenge of reducing their child's excess weight." The Connect 4 Health trial was conducted from June 2014 through March 2016 at six Harvard Vanguard pediatric practices in th...